Vitamin K deficiency could contribute towards bleeding disorder and osteoporosis

Vitamin K deficiency can occur in any age group and exists when chronic failure to eat sufficient amounts of vitamin K. It results in a tendency for spontaneous bleeding or in prolonged and excessive bleeding with trauma or injury. Vitamin K deficiency can result in bleeding gums, and in skin that is easily bruised. The protein in the body most affected by vitamin K deficiency is a blood-clotting protein called prothrombin.

Vitamin K plays aMulti Vitamin for Men Reviewn important role in blood clotting. Without the vitamin, even a small cut would cause continuous bleeding in the body, and death. Blood clotting is a process that begins automatically when any injury produces a tear in a blood vessel. The clotting factors are proteins. These proteins require vitamin K for their synthesis in the body. The blood-clotting process also requires a dozen other proteins that do not need vitamin K for their synthesis.

When Vitamin K deficiency occurs, it is found in people with diseases that prevent the absorption of fat. These diseases include cystic fibrosis, celiac disease, and cholestasis. Vitamin K deficiency can exist in adults treated with antibiotics that kill the bacteria that normally live in the digestive tract. Because the intestine-bacteria supply part of our daily requirement of vitamin K.

Vitamin K is an essential lipid-soluble vitamin that plays a vital role in the production of coagulation proteins. Vitamin K is also synthesised by colonic bacteria.

Vitamin K is also very important for bone health. Because vitamin K is involved in gamma carboxylation of osteocalcin, which is important in bone synthesis, osteoporosis is associated with Vitamin K deficiency. Its deficiency shows up as bone-related problems like loss of bone (osteopenia), decrease in bone mineral density (osteoporosis), and fractures including hip fractures. Vitamin K deficiency is thought to cause impaired activation of bone matrix protein osteocalcin, and reduction of osteoblast function, resulting in impaired bone formation.

Deficiency of vitamin K leads to a reduction in the prothrobin content of blood. If you are deficient in vitamin K, you will suffer from blood clotting as gum bleeding, nose bleeding, and easy bruising. Symptoms and signs of vitamin K deficiency further include bleeding within the digestive tract and blood in the urine.

Other prominent signs and symptoms of vitamin K deficiency are prolonged clotting times, hemorrhaging, and anemia. Deficiency of vitamin K can also lead to Alzheimer’s disease.

Hardening of the arteries or calcium-related problems are the other common signs of vitamin K deficiency. So are biliary obstruction, malabsorption, cystic fibrosis, and resection of the small intestine.

Vitamin K deficiency can be prevented by consuming an appropriate diet.

Vitamin K is found in green leafy vegetables and oils, such as olive, cotton seed, and soya bean. Other foods rich in vitamin K are green peas and beans, watercress, asparagus, spinach, broccoli, oats and whole wheat.

 

What are the effects of vitamin E deficiency?

The main symptoms of vitamin E deficiency are hemolytic anemia and neurological deficits.

Multi Vitamin for Men ReviewVitamin E deficiency causes fragility of red blood cells and degeneration of neurons, particularly peripheral axons and posterior column neurons. Vitamin E deficiency mainly arises from fat malabsorption. Low birth weight can also cause vitamin E deficiency.

Vitamin E deficiency is a very rare problem. It causes neurological problems due to poor nerve conduction. When vitamin E deficiency does occur, it strikes people with diseases that prevent the absorption of dietary fats and fat-soluble nutrients. Since vitamin E is a fat-soluble vitamin, it has some of the properties of fat.

Vitamin E seems to have only one function in the body: the prevention of the natural and continual process of deterioration of all body tissues. This deterioration is provoked by a number of causes; one of these is toxic oxygen. During the body’s metabolism of atmospheric oxygen, toxic oxygen is produced continuously in the body by the formation of by-products. These toxic by-products include hydrogen peroxide, superoxide, and hypochlorite.

Hypochlorite is a natural product, produced by cells of the immune system. It is also the active component of bleach. Once formed, toxic oxygen can damage various parts of the body, such as the membranes which form the boundaries of every cell. Vitamin E serves the body in protecting membranes from toxic oxygen damage. In contrast, vitamin C serves to protect the aqueous, or watery, regions of the cell from toxic oxygen damage. The membranes that are most sensitive to toxic oxygen damage are the membranes of nerves; therefore, the main symptom of vitamin E deficiency is damage to the nervous system.

In developing countries, the most common cause is inadequate intake of vitamin E. In developed countries, the most common causes are disorders that cause fat malabsorption, including cystic fibrosis, pancreatitis, and cholestasis (bile-flow obstruction). Bile salts, produced in the liver, are required for the absorption of fats. Cholestasis causes a decrease in the formation of bile salts and the consequent failure of the body to absorb dietary fats. For this reason, this disease may result in vitamin E deficiency.

Vitamin E deficiency may contribute to retinopathy of prematurity in premature infants and to some cases of intraventricular and subependymal hemorrhage in neonates. Affected premature neonates have muscle weakness.Multi Vitamin for Men Review

Another symptom of early vitamin E deficiency in children with cystic fibrosis is a decline in cognitive function, which results in difficulty with reading and falling behind in other intellectual skills during the elementary school years. Researchers have urged the introduction of neonatal screening in order to offset the potential effects of early vitamin E deficiency.

Vitamin E deficiency in humans results in ataxia (poor muscle coordination with shaky movements), decreased sensation to vibration, lack of reflexes, and paralysis of eye muscles. One particularly severe symptom of vitamin E deficiency is the inability to walk.

Attention has been given to the theory that vitamin E serves to protect against cancer and atherosclerosis.